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Posted by Elizebath Bijoy Sunday, March 25, 2012

Washington: Nanoparticle-sized Chitosan has shown promise in effectively combating Staphylococcus saprophyticus and E. coli.

Chitosan is a natural, non-toxic and biodegradable, obtained from chitin, the main component of the shells of shrimp, lobster and the beak of the octopus and squid.

It could be used as a protective wound-healing material to avoid opportunistic infection as well as working to facilitate wound healing, the International Journal of Nano and Biomaterials reports.

Mihaela Leonida of Fairleigh Dickinson University, in Teaneck, New Jersey, colleagues reported how they have prepared nanoparticles of chitosan that could potentially preventing infection in wounds as well as enhancing the wound-healing by stimulating skin cell growth.

Understanding the mechanism of inhibition of bacteria by these particles may lead to the preparation of more effective antibacterial agents, according to a Fairleigh University statement.

S. saprophyticus infects the urinary tract. Symptoms are burning sensation when passing urine, the urge to urinate more often than usual, the 'dripping effect' after urination, weak bladder, bloated feeling with sharp razor pains in the lower abdomen around the bladder and ovary areas, etc.

Most strains of E. coli, commonly found in the lower intestine of warm-blooded organisms are harmless, but some serotypes can cause serious food poisoning in humans. 


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