Followers

Total Pageviews

There was an error in this gadget
Jaiho- Dubai. Powered by Blogger.
There was an error in this gadget

FAMILY HISTORY UPS LIVER CANCER

Posted by Elizebath Bijoy Wednesday, April 25, 2012

Those who have a positive family history of liver cancer are more likely to develop hepatocellular carcinomas (HCC), a new study has suggested.

The study also showed 70-fold elevated risk of HCC in those with liver cancer in the family and markers for hepatitis B (HBV) or hepatitis C(HCV).
Liver cancer ranks sixth in incidence and the third cause of mortality worldwide.
According to the World Health Organization (WHO) liver cancer was responsible for 700,000 deaths in 2008, with HBV and HCV accounting for 78 percent of all cases of HCC.


A vaccine for HBV has been available since 1982; however prior studies have shown familial clustering of HCC in East Asia where HBV is common. While medical evidence reports family history to be related to HCC risk, little is known of this relationship in non-Asian populations.


"There is a high incidence of liver cancer in southern Italy which is likely a result of a higher frequency of HCV in this area," explained Professor Carlo La Vecchia from the Istituto di Ricerche Farmacologiche "Mario Negri" and the University of Milan in Italy.


"Our study investigated the relationship between family history and liver cancer in a Western population," he stated.The case-control study was carried out between January 1999 and July 2002, and included 229 cases of HCC and 431 hospital controls. HCC patients ranged in age from 43 to 84 years, providing survey information and blood samples.


The control group included patients admitted to hospital for conditions not related to tumours. Analysis of data on family history and liver cancer updated to April 2011 was also performed.Results show that 75 percent of the cases and 11 percent of controls showed evidence of HBV and HCV infection.
Family history of liver cancer was associated to HCC risk after adjusting for chronic HBV and HCV. Compared to subjects without family history of liver cancer and no chronic HBV and HCV, researchers reported an odds ratio of 73 for those with both risk factors, indicating a 70-fold increased risk of developing HCC.


"Our findings confirm that individuals with a positive family history of liver cancer have three times higher risk of developing HCC," noted Professor La Vecchia."Monitoring individuals with family history, particularly those with hepatitis markers, could help to identify HCC at an earlier stage, and hence potentially reduce mortality from HCC," he suggested.The findings were published in the May issue of Hepatology, a journal of the American Association for the Study of Liver Diseases.

0 comments

Post a Comment

About Me

My photo
Dubai, United Arab Emirates
Warm welcome to my health blog! This was introduced with an objective to educate and spread awareness among people, encouraging them to live healthier lives with longevity. Let me emphasize that our contemporary situation in individual’s life are so fast moving that we tend to neglect and spare some moments for our own health. My inspiration has turned into passion in a health care that turned into a blog. The ample of support and response was tremendously changed into positive results. I dedicated this blog for all those people who are very conscious for their health and life style. Hope so, I can bring differences for healthy living the fore my viewer comments are always valuable and your continued patronage is important for me. Wish you a happy and healthy life ahead!

SHARE

BMI Calculator

live traffic feed

DAILY BRAIN GAME